Lisdexamfetamine in combination with guanfacine as an effective treatment in the management of behavioral disturbances in patients with Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Case report

Introduction We often find it challenging to manage hyperactivity, low frustration tolerance and angry outbursts in patients with ASD comorbid ADHD. Fewer drugs are approved for these disorders more likely develop adverse effects. Objectives The aim of this case is show how the combination lisdexamfetamine together guanfacine has very positive effects on anger boundary heteroaggressiveness Methods Case report literature review Results This a 14-year-old minor admitted psychiatric unit after physical aggression against his family due removal video games, requiring police intervention. He been diagnosed since he was 11 years old ADHD Autism Spectrum Disorder. being treated methylphenidate 54 mg aripiprazole 10 mg. Since beginning admission, following pharmacological adjustment made: Methylphenidate substituted by up 50 per day. Guanfacine started 4 day dose maintained. patient had no adequate without sedation, hyporexia or hypotension. With adjustment, improvement found levels restlessness hyperactivity. expressed subjective notable attention hospital classroom. An emotional regulation also observed, imposition limits, an explosion face any rule during admission Conclusions management hyperactivity episodes complex. Many studies point out time-limited use some antipsychotics such as risperidone aripiprazole. work aims excellent agitation rage patients. In addition, profile at metabolic level much better than that atypical antipsychotics. Reference - Extended-Release Hyperactivity Children Lawrence Scahill et al. Am J Psychiatry. 2015 Dec. Disclosure Interest None Declared